The second generation of Kirksey doctors was Dr. Robert J. Kirksey, the son of Dr. C. L. Kirksey. Robert graduated from the college of Physicians and Surgeons in Baltimore in 1891. He migrated to Cross Creek, South Carolina, then to Oenaville, Texas then back to Dover, Arkansas. He practiced many years there and then moved to Owasso, Oklahoma where he continued his medical practice until he died.